Defining a novel subset of CD1d‐dependent type II natural killer T cells using natural killer cell‐associated markers
نویسندگان
چکیده
منابع مشابه
Cytokine-induced killer cells are type II natural killer T cells
BACKGROUND Until now, cytokine-induced killer (CIK) cells were assumed to be part of the type I natural killer T (NKT) cell population, but it was not yet investigated if this is correct. METHODS For analysis, CIK cells were generated by various culture conditions. Human type I NKT cells express a T cell receptor (TCR) composed of an invariant V alpha 24-J alpha Q chain combined with one of s...
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Invariant Natural killer T cell (iNKT cells) are a subset of T cells, which are narrowly defined as a T cell lineage expressing a semi-invariant CD1d-restricted T cell Receptors (TCRs) composed by Vα24-Jα18/Vβ11 in human, and Vα14-Jα18/Vβ8,Vβ7, and Vβ2 in mouse. Unlike conventional T cells which recognize peptides bound to highly polymorphic major histocompatibility complex (MHC) class I and II...
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ژورنال
عنوان ژورنال: Scandinavian Journal of Immunology
سال: 2019
ISSN: 0300-9475,1365-3083
DOI: 10.1111/sji.12794